Life, the universe and everything?
Maybe
A really esoteric bit of mathematics, the "Reimann hypothesis", has been around for ages and, if the equations are solved, appears to show a relationship between the distribution of prime numbers and Quantum mechanics - pretty much how the unvierse works.
The first two numbers of the Reimann sequence have been known for a long time, they're 1 and 2.
In 1996 a Bristol university team found the missing number - "the third moment of the Reimann zeta function".
it's 42
Gulp